Meaghan O'Malley Morris,MD, PHD
Assistant Professor, Neuropathology
Specialization: Alzheimer’s disease and dementia, Microtubule-associated protein Tau, Aging
Contact
Johns Hopkins University School of Medicine
720 Rutland Avenue
Ross bldg., Room 558
Baltimore, MD 21205
Our research focuses on understanding the molecular basis for Alzheimer’s disease and other age-related dementias. These investigations combine insights from human brain tissue donated by patients with age-related neurodegenerative diseases, studies in cell culture models, and molecular techniques to uncover new pathways involved in Alzheimer’s disease and other neurodegenerative diseases.
Tau has been implicated in regulating neuronal network activity in the brain and the removal of tau makes mice resistant to seizure activity. Our lab uses cell culture models to uncover the novel roles of tau in neuronal biology, with a focus on the interaction between tau and neuronal activity. Tau has been implicated in regulating neuronal network activity in the brain and the removal of tau makes mice resistant to seizure activity. Our lab uses cell culture models to uncover the novel roles of tau in neuronal biology, with a focus on the interaction between tau and neuronal activity